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( A ) Representative SCC-61 and rSCC-61 tumors measured by our optical spectroscopy; ( B ) Tumor volumes of SCC-61 and rSCC-61 tumors on day 10 post cell injection; ( C ) Average diffuse <t>reflectance</t> spectra measured on all five in vivo SCC-61 tumors and five in vivo rSCC-61 tumors; ( D ) MC model extracted absorption coefficients of five in vivo SCC-61 tumors and five in vivo rSCC-61 tumors; ( E ) MC model extracted reduced scattering coefficients of five in vivo SCC-61 tumors and five in vivo rSCC-61 tumors. Tumor volume was estimated using the equation: volume = (Length x Width x Height)/2.
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( A ) Representative SCC-61 and rSCC-61 tumors measured by our optical spectroscopy; ( B ) Tumor volumes of SCC-61 and rSCC-61 tumors on day 10 post cell injection; ( C ) Average diffuse <t>reflectance</t> spectra measured on all five in vivo SCC-61 tumors and five in vivo rSCC-61 tumors; ( D ) MC model extracted absorption coefficients of five in vivo SCC-61 tumors and five in vivo rSCC-61 tumors; ( E ) MC model extracted reduced scattering coefficients of five in vivo SCC-61 tumors and five in vivo rSCC-61 tumors. Tumor volume was estimated using the equation: volume = (Length x Width x Height)/2.
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( A ) Representative SCC-61 and rSCC-61 tumors measured by our optical spectroscopy; ( B ) Tumor volumes of SCC-61 and rSCC-61 tumors on day 10 post cell injection; ( C ) Average diffuse reflectance spectra measured on all five in vivo SCC-61 tumors and five in vivo rSCC-61 tumors; ( D ) MC model extracted absorption coefficients of five in vivo SCC-61 tumors and five in vivo rSCC-61 tumors; ( E ) MC model extracted reduced scattering coefficients of five in vivo SCC-61 tumors and five in vivo rSCC-61 tumors. Tumor volume was estimated using the equation: volume = (Length x Width x Height)/2.

Journal: Biomedical Optics Express

Article Title: Multi-parametric functional optical spectroscopy to monitor the metabolic and vascular changes in small head and neck tumors in vivo with radiation stress

doi: 10.1364/BOE.565339

Figure Lengend Snippet: ( A ) Representative SCC-61 and rSCC-61 tumors measured by our optical spectroscopy; ( B ) Tumor volumes of SCC-61 and rSCC-61 tumors on day 10 post cell injection; ( C ) Average diffuse reflectance spectra measured on all five in vivo SCC-61 tumors and five in vivo rSCC-61 tumors; ( D ) MC model extracted absorption coefficients of five in vivo SCC-61 tumors and five in vivo rSCC-61 tumors; ( E ) MC model extracted reduced scattering coefficients of five in vivo SCC-61 tumors and five in vivo rSCC-61 tumors. Tumor volume was estimated using the equation: volume = (Length x Width x Height)/2.

Article Snippet: All raw diffuse reflectance spectra were calibrated using a 20% reflectance standard (Spectralon, Labsphere) before quantitative analysis.

Techniques: Spectroscopy, Injection, In Vivo

Tumor volumes of SCC-61 (A) and rSCC-61 (E) tumors prior to and post RT. Average diffuse reflectance spectra measured on SCC-61 (B) and rSCC-61 tumors (F) , the MC model extracted absorption coefficients of SCC-61 (C) and rSCC-61 (G) tumors and the MC model extracted reduced scattering coefficients of SCC-61 (D) and rSCC-61 (H) tumors prior to and post radiation treatment. Tumor volume was estimated using the equation: volume = (Length x Width x Height) / 2. One animal from the SCC-61 group showed obvious tumor necrosis, therefore, the animal was euthanized before RT treatment per IACUC protocol.

Journal: Biomedical Optics Express

Article Title: Multi-parametric functional optical spectroscopy to monitor the metabolic and vascular changes in small head and neck tumors in vivo with radiation stress

doi: 10.1364/BOE.565339

Figure Lengend Snippet: Tumor volumes of SCC-61 (A) and rSCC-61 (E) tumors prior to and post RT. Average diffuse reflectance spectra measured on SCC-61 (B) and rSCC-61 tumors (F) , the MC model extracted absorption coefficients of SCC-61 (C) and rSCC-61 (G) tumors and the MC model extracted reduced scattering coefficients of SCC-61 (D) and rSCC-61 (H) tumors prior to and post radiation treatment. Tumor volume was estimated using the equation: volume = (Length x Width x Height) / 2. One animal from the SCC-61 group showed obvious tumor necrosis, therefore, the animal was euthanized before RT treatment per IACUC protocol.

Article Snippet: All raw diffuse reflectance spectra were calibrated using a 20% reflectance standard (Spectralon, Labsphere) before quantitative analysis.

Techniques: